Evaluation of Hepatotoxicity in the Human In Vitro HepG2 Model After Exposure to Ten Individual UV Filters, and Six Sunscreen Products After Ex Vivo Pig Skin Permeation
Ultraviolet (UV) filters can cross the skin barrier and enter the body. This in vitro study aimed to assess whether UV filters used in sunscreen products could be hepatotoxic. Human HepG2 liver cells were exposed for 48 h at human relevant concentrations (0.5–100 µM) to ten individual UV filters and transdermal fractio...