Steven R. Smith

Impaired adipogenesis and lipid storage capacity in subcutaneous adipose tissue of patients with PMOS

Women with PMOS (formally termed PCOS) have an overall increased prevalence of metabolic syndrome (MetS) and central obesity. To help determine whether there might be changes in s.c. adipose tissue (SAT) associated with these abnormalities, we performed single-nuclei and scRNA-seq on SAT biopsies from 15 premenopausal...