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Author

Stephen Y. Lai

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Review Open access Sep 2026

The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet their clinical impact is limited by immune-related adverse events (irAEs), therapeutic resistance, and the lack of reliable predictive biomarkers, contributing to a shift from early promise to a therapeutic plateau. irAEs affect multiple organ sys...

Joud Hajjar, B. Stephen, A. Aaroe et al. · 1 citation
Open access Aug 2026

TERT Promoter Variants, Older Age, and Prognosis in Papillary Thyroid Carcinoma.

The findings of this cohort study suggest that the high prevalence of TERT promoter variants in older patients largely explains the association between age and worse prognosis in PTC.

V. R. Marczyk, Sophie Li, Chia C. Wu et al. · 0 citations

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