Author

Stephen L. Kates

2 papers indexed here

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Open access Aug 2026

Immune checkpoint molecules as biomarkers of Staphylococcus aureus bone infection and clinical outcome

Staphylococcus aureus prosthetic joint infections (PJIs) are broadly considered incurable, and clinical diagnostics that guide conservative vs. aggressive surgical treatments don’t exist. Understanding the human T cell response to chronic S. aureus osteomyelitis may lead to improved patient outcomes and info...

Motoo Saito, Katya A. McDonald, Alexander Grier et al. · Communications Medicine · 0 citations

Open access Jul 2026

T cell dysfunction during Staphylococcus aureus osteomyelitis in humanized mice 2257659

Staphylococcus aureus is the leading cause of implant-associated osteomyelitis. It has a high recurrence rate, a low post-operative cure rate, and can lead to sepsis, multiorgan failure, and death. This indicates a need for future innovation in therapeutics and vaccines. With our humanized mouse model, we aimed t...

Katya A. McDonald, Motoo Saito, Himanshu Meghwani et al. · Journal of Immunology · 0 citations