Author

Stephanie M. Correa

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Open access Sep 2026

Targeting estrogen to the brain via DHED does not seem to protect against metabolic dysfunction in obese OVX mice

Abstract Menopausal hormone therapy (MHT), prescribed for climacteric symptoms including hot flushes and weight gain, contains estrogens such as 17 beta-estradiol (17βE2). However, estrogen receptor activation by MHT may increase reproductive cancers in some people. As the protective metabolic effects of 17βE2 are part...

Celine Camon, Elodie Kip, R. Lord et al. · Endocrinology · 0 citations

Open access Aug 2026

Endocrine-Adapted Pituitary Macrophages Regulate Gonadotropin Secretion through CXCL5-CXCR2-MAPK Signaling

Chronic inflammation disrupts hormonal balance in the Hypothalamic-Pituitary-Gonadal (HPG) axis, contributing to reproductive disorders. While immune cells in the hypothalamus and ovaries have been extensively studied, their impact on the pituitary remains largely unexplored. Our research identifies pituitary macrophag...

Z. Del Mundo, J. Ha, Lily Zhou et al. · bioRxiv · 0 citations