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Author

Stefano Serra

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Open access Sep 2026

From Chemoenzymatic Synthesis to Biological Effects: Enantiomerically Enriched Vanillin-Derived δ-Iodo-γ-Lactones as Modulators of Cancer Cell Viability and Inducers of Cell Death

Enantiomerically enriched vanillin-derived cis- and trans-β-aryl-δ-iodo-γ-lactones were synthesized using a chemoenzymatic pathway based on Candida antarctica lipase B (CALB)-catalyzed transesterification of racemic (E)-4-(4′-benzyloxy-3′-methoxyphenyl)but-3-en-2-ol, followed by Claisen rearrangement, hydrolysis, iodol...

Anna Dunal, D. Poradowski, Stefano Serra et al. · 0 citations
Open access Jul 2026

Whole-Cell Fungal Biotransformation of para-Hydroxycinnamic Acids Mediated by Phenolic Acid Decarboxylase, Carboxylic Acid Reductase and Alcohol Dehydrogenase

The results highlight endophytic fungi as largely untapped and versatile biocatalysts for pHCA biotransformation and establish whole-cell fungal systems as robust, non-recombinant alternatives to engineered platforms.

A. Baskaran, Stefano Serra, El-Sayed R. El-Sayed et al. · 1 citation

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