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Author

Stefano Alcaro

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2 papers indexed here

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Open access Sep 2026

In silico-guided design, synthesis and in vitro evaluation of thiazolo-pyridines targeting SARS-CoV-2 Nsp13.

In the search for novel antiviral agents targeting SARS-CoV-2 non-structural protein 13 (Nsp13), we applied an integrated in silico drug design workflow combining ADME profiling, molecular interaction field analysis, molecular docking and thermodynamic evaluations to identify thiazolo-pyridine derivatives as promising...

R. Bivacqua, Roberta Emmolo, Gianmarco Gualtieri et al. · 0 citations
Sep 2026

Rational design of hybrid hydrazide-hydrazone/thiourea derivatives as potential VEGFR-2 targeting anticancer agents: synthesis, biological evaluation, and mechanistic insights into anticancer activity.

The development of novel anticancer agents capable of modulating pathways associated with tumor progression remains a critical strategy, particularly for aggressive breast cancer subtypes such as triple-negative breast cancer (TNBC). In this study, a new series of hydrazide-hydrazone/thiourea derivatives (MIH-31-46) wa...

Guzide Satir-Basaran, Ahmed Amleh, Antonio Curcio et al. · 0 citations

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