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Author

Stefan Scholten

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Open access Sep 2026

RISC-bound small RNA sequencing provides insights into guide-strand selection and siRNA trimming and tailing following insecticidal dsRNA delivery

RNA interference (RNAi) offers a sequence-specific approach to pest control. In insects, Dicer-2 processes double-stranded RNA (dsRNA) into small interfering RNA (siRNA) duplexes, from which the RNA-induced silencing complex (RISC) retains a guide strand. However, how the sequence of delivered dsRNA shapes the RISC-bou...

Gözde Güney, Paul Plathner, Stefan Scholten et al. · 0 citations

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