Measurements of Liver and Bone Marrow Proton Density Fat Fraction in the Setting of Ferumoxytol-Enhanced MRI.
BACKGROUND Proton density fat fraction (PDFF) is typically measured using confounder-corrected, multi-echo, gradient-recalled-echo chemical-shift-encoded (CSE)-MRI. Ferumoxytol, an iron-based MRI contrast agent, increases liver and bone marrow (BM) R2*, a major confounder of PDFF. PURPOSE To assess the impact of feru...