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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Song-Bo Xie

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Sep 2026

Targeted dual degradation of GPC-3 and VEGFR with multivalent DNA nanoflower-based LYTACs for hepatocellular carcinoma therapy.

While targeted therapies for hepatocellular carcinoma (HCC) have advanced, their clinical benefits remain constrained by limited efficacy, off-target toxicity, and the frequent emergence of drug resistance and recurrence. To address these challenges, we developed a multivalent DNA nanoflower-based dual-targeting LYTAC...

Ping Zhou, Jin-Zhi Zang, Jia-Xuan Wang et al. · 0 citations
Review Sep 2026

BioPROTACs: a promising approach for targeted protein degradation.

The molecular mechanisms, recent advances, and emerging applications of bioPROTAC technology are summarized, the current technical challenges are evaluated, potential strategies to address these limitations are discussed, and future directions that may facilitate its clinical translation are highlighted.

Yu-Yang Li, Fu-Ru Zhang, Ren-Shuai Zhang et al. · 0 citations

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