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Author

Sokchea Lay

2 papers indexed here

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Review

The role of epitope-specific antibodies and Fc effector functions in determining disease severity during secondary dengue virus infection

Dengue remains the most prevalent vector-borne disease globally and poses a significant global public health challenge. Despite this, no universally adopted vaccine or targeted antiviral therapy currently exists. While most infections cause mild or no symptoms, some individuals develop severe disease, particularly when...

Sokchea Lay · 0 citations
#protein folding Open access Oct 2026

Quantitative and qualitative differences in anti-Envelope IgG-secreting cells distinguish subclinical and hospitalized dengue in a Cambodian pediatric cohort.

Dengue virus (DENV) infection can result in outcomes ranging from subclinical disease to life-threatening illness, yet the antibody features mediating protection in humans remain poorly defined. Dengue virus envelope protein (E) forms homodimers on the virion surface and elicits both neutralizing and non-neutralizing a...

Amandine Trouchet, Sokchea Lay, Matteo Broketa et al. · 0 citations

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