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Author

Soham Maity

2 papers indexed here

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Open access Sep 2026

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

ABSTRACT Salmonella infections are a major global health burden, exacerbated by rampant antimicrobial resistance and the narrow serovar coverage of current vaccines. To overcome the limitations of current vaccine design, structurally defined trisaccharides derived from Salmonella O‐polysaccharide backbones composed of...

Xing-Ling Pan, Soham Maity, H. Kavunja et al. · 0 citations
Sep 2026

Discovery of Tetrasubstituted Quinazolin-4(3 H )-ones as Wild-type-sparing, Highly Selective PI3KαH1047R Inhibitors

Inhibiting PI3Kα has demonstrated promising therapeutic effects for patients with HR+/HER2− and PIK3CA-mutated advanced or metastatic breast cancer. However, hyperglycemia and other notable adverse events (AE) associated with concomitant wild-type inhibition remain a challenge and limit dosing. Selectively targeting...

Chun Chen, R. Holmes, Jack Carter et al. · 0 citations

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