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Author

Sofia Benavides

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Open access Aug 2026

Single-cell transcriptomics provides insights into the stress-immune interplay and informs disease risk

An ex vivo model investigating the transcriptomic responses of primary peripheral blood mononuclear cells and neutrophils to physiological stress levels of cortisol and norepinephrine at single-cell resolution provides cell-type-level insights into how stress hormones modulate immune function relevant to human health.

Sofia Benavides, Oksana Kosyk, Haiyang Wang et al. · 1 citation
Open access Aug 2026

Stress-Related Methylation Risk Scores Predict Coronary Heart Disease

This study supports methylation risk scores as novel biomarkers of stress-related CHD and uncovers epigenetic regulation in monocytes as a potential underlying mechanism of stress-related CHD, highlighting biological pathways linking stress and disease and may promote personalized interventions in high-risk populations...

Sofia Benavides, Hazel Milla, Helena Palma-Gudiel et al. · 0 citations

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