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Author

Sisi Zhang

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Sep 2026

An Integrated Workflow for Improving Thermostability: Mechanism and Engineering of GH11 Xylanases via Ser/Thr Substitutions.

Thermostability is critical yet challenging to engineer in industrial enzymes. Here, we present an integrated workflow for enhancing the thermostability of GH11 xylanases through systematic Ser/Thr optimization. Gibbs free energy calculations on XynCDBFV identified 169 stabilizing single-site mutations involving Ser/Th...

Yuan-Yuan Zhe, Sisi Zhang, En-Heng Zhu et al. · 0 citations

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