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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Sini Pitkänen

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Open access Aug 2026

Mechanical Activation of Piezo1 by Virus-like Nanospikes to Potentiate STING-driven Macrophage Reprogramming

Virus-like nanotopography is reported as a previously unrecognized regulator of Piezo1-mediated mechanotransduction in macrophages using virus-like mesoporous silica nanoparticles (VLPSi) with tunable rigid nanospike lengths, providing a biomimetic strategy for enhancing the M1 polarization of macrophage through the co...

Jia-Jia Wang, Minna Sivonen, E. Batnasan et al. · 0 citations

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