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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Sinan Karageçili

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Sep 2026

Fragment-Based AI Optimization of Tranexamic Acid Derivatives Targeting the Kringle 1 Lysine-Binding Site of Human Plasminogen: An Integrated Computational Study for Postpartum Hemorrhage

Postpartum hemorrhage remains a leading cause of maternal mortality worldwide, frequently associated with excessive fibrinolysis mediated by plasminogen activation. Tranexamic acid (TXA) is widely used as an antifibrinolytic agent; however, optimization of its scaffold may improve binding characteristics and pharmacolo...

Sinan Karageçili, Deniz Inan, Nouman Ali · 0 citations

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