Author

Simon Schrott

2 papers indexed here

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Open access Aug 2026

RNA-dependent association of the pyruvate dehydrogenase complex with mtDNA-containing assemblies supports mitochondrial translation

Mitochondrial DNA (mtDNA) encodes core subunits of the oxidative phosphorylation machinery, and its expression is spatially organized, with the genome packaged into nucleoids around which transcription and mitoribosome assembly are concentrated. How this architecture is built, and how it is linked to the metabolic stat...

Johannes Hagen, Nupur Sharma, Felix Thoma et al. · bioRxiv · 0 citations

Open access Jul 2026

Nanobody-based Tools for in-depth Research of Immuno-Oncology Targets 2334607

Immuno-oncology is a rapidly growing field with an urgent need for well-characterized and highly specific research reagents, particularly in immune checkpoint targeting and acute myeloid leukemia (AML). We have developed recombinant monoclonal nanobodies (VHHs) targeting these critical areas to facilitate researc...

Annika V. Dalheim, S. Wendler, L. Yurlova et al. · Journal of Immunology · 0 citations