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Author

Silvia Gregori

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Open access Sep 2026

Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity

Chemotherapy resistance and disease relapse are major determinants of treatment failure in acute myeloid leukemia (AML). Therapy-induced senescence (TIS) is one outcome of chemotherapy, but its immunological consequences in AML remain unclear. Here we show that ex vivo chemotherapy induces senescence in a subset of the...

Diego Gilioli, Simona Fusco, Teresa Tavella et al. · 0 citations
Open access Aug 2026

Superior precision of clinical predictions after CD3-relativisation to align flow cytometry data

A benchmark flow cytometry dataset assembled using 6 cytometers at 4 independent laboratories in Spain and Germany establishes a robust standard for evaluating computational methods in clinical cytometry, especially their stability over time and generalisability between instruments, laboratories and clinically heteroge...

Gunther Glehr, K. Kronenberg, Fabiola Arella et al. · 0 citations

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