Silke Mortelmans

Leishmania infantum triggers lipid peroxidation and non-canonical cell death in macrophages.

Leishmania infantum is a causative agent of visceral leishmaniasis and survives as an obligate intracellular parasite within macrophages by modulating host cell death pathways. While preservation of host cell viability is critical for parasite replication, infected macrophages ultimately undergo cell death, although th...