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Si-Xiang Xu

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Open access Oct 2026

Spontaneous wbbL and waaG mutations selected by phage vB_EcoP_P61425 confer resistance and attenuate virulence in ExPEC

Bacteriophage therapy is a promising strategy against multidrug-resistant (MDR) extraintestinal pathogenic Escherichia coli (ExPEC), yet bacterial resistance evolution remains a major clinical challenge. In this study, we isolated and comprehensively characterized a novel lytic phage, vB_EcoP_P61425, belonging to t...

Long Chen, Si-Xiang Xu, Xiao-Yue Li et al. · 0 citations

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