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Author

Siwei Song

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Open access Aug 2026

Predicting PD-L1+ CD8− status in non-small cell lung cancer tissue from clinical indicators using machine learning

Abstract Background: Programmed death-ligand 1 (PD-L1) expression and CD8-positive (CD8+) T-cell infiltration in tumor tissue are associated with prognosis in non-small cell lung cancer (NSCLC). However, the prognostic value of combined PD-L1/CD8 immune phenotyping in surgically treated NSCLC and the feasibility of pre...

Si-Wei Song, Yan-Ling Ma, Zhe Jia et al. · 0 citations
Review Open access Jul 2026

Regulatory role of protein lactylation in tumor metastasis: mechanisms and emerging therapeutic strategies.

This review discusses how lactylation operates within a broader post-translational modification (PTM) network through crosstalk with acetylation, ubiquitination, and RNA methylation to amplify oncogenic signaling.

Xinyue Yu, Si-Wei Song, Yingji Ke et al. · 1 citation

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