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Author

Si-Fu Yang

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Case report Open access Sep 2026

Complete pathological response after neoadjuvant chemoimmunotherapy in PD-L1-negative unresectable primary hepatic small cell carcinoma: a case report and tumor microenvironment analysis

Background Primary hepatic small cell carcinoma (PHSCC) is an extraordinarily rare and aggressive malignancy with a dismal prognosis. No standard treatment exists, and the role of immunotherapy in this tumor type, especially in programmed cell death ligand 1 (PD-L1) negative cases, remains unexplored. Case presentation...

Yu-Peng Hong, Si-Fu Yang, Yu-Chen Zhong et al. · 0 citations

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