This review extends beyond a predominantly WNT-centered view of sFRP2 and proposes a context-stratified framework for biomarker interpretation and therapeutic targeting based on cellular origin, dominant signaling axis, disease stage, and tissue compartment.
Xiao-Ping Luo, Mian Li, Yi Huang et al.· Frontiers in Cell and Develo...· 0 citations
This review critically synthesizes recent advances in TCM for HUA, focusing on how natural products modulate uric acid production, renal/intestinal excretion, inflammation, and gut microbiota via the gut–kidney axis, and proposes a four-tier hierarchical framework that bridges molecular precision with systemic effects.
Hong Li, Si-Qi You, Xiao-Ping Luo et al.· Frontiers in Pharmacology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.