Open access
Oct 2026
Combined HDAC and ATM inhibition with radiation in preclinical glioblastoma models
Susan Qualls-Histed, K. Chung, G. Uzunalli et al.
· bioRxiv · 0 citations
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Sep 2026
Vascularized glioblastoma-on-a-chip reveals microglia-mediated regulation of tumor invasion and stemness.
Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor in adults, characterized by rapid progression and poor prognosis. Central to GBM pathobiology are glioma stem cells (GSCs), which preferentially localize within the perivascular niche (PVN) and sustain tumor growth, invasion, and therapeutic resis...
Twinkle Jina Minette Manoharan, K. Ravi, Shwetal Mehta et al.
· Lab on a Chip · 0 citations