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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Shuya Fukai

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Open access Sep 2026

RAB1 mediates OPTN-dependent mitophagy via ATG9A recruitment.

Damaged mitochondria are selectively eliminated through mitophagy, a critical quality control process. A kinase PINK1 and an E3 ubiquitin ligase PRKN/Parkin, both of which are mutated in familial Parkinson disease, amplify ubiquitin signals on the damaged mitochondria. The autophagy receptor OPTN plays a pivotal role i...

Waka Kojima, Ryu Endo, Kei Okatsu et al. · 0 citations

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