An outbreak of ebolavirus disease caused by a new zoonotic spillover of Bundibugyo virus (BDBV) is currently spreading at an unprecedented pace in the Democratic Republic of the Congo and Uganda. The outbreak has resulted in 7,733 cases with a case-fatality ratio of 48%, yet no BDBV-specific vaccines or therapeutics ar...
Amin Addetia, K. Uriu, Cameron Stewart et al.· bioRxiv· 0 citations
A practical framework linking sites, structure, and serology for viruses in which antigenic evolution is a major component of immune escape and lineage turnover is outlined and how integrating genomic surveillance data, phylogenetics, structural analysis, and predictive modeling could support more prospective variant a...
Sanni Översti, Spyros Lytras, Shusuke Kawakubo et al.· Journal of Virology· 0 citations
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