Review
Open access
Jul 2026
Targeting the deubiquitinase USP28 in cancer: navigating context-dependent mechanisms and therapeutic resistance
A review of the molecular characteristics and physiological functions of USP28, its context-dependent roles in neoplastic diseases, and its translational implications for targeted therapy and biomarker discovery highlights its potential as a therapeutic target for precision medicine.
Tongyong Luo, Shuncai Wu, Qing-Song Wang et al.
· Frontiers in Immunology · 1 citation