2026
Production of Cell Models with Differential Zygosity Using CRISPR Base Editors.
A detailed protocol for performing gene editing using an adenine base editor (ABE) to induce a single A-G transition mutation in a gene of therapeutic relevance is provided, enabling the production of cell models suited to the study of both dominant and recessive mutations.
Shun Zhang, B. P. Hubbard
· Methods in molecular biology · 0 citations