Shun-Yong He

miR-885-5p regulates fibrogenic phenotypes in TGF-β1-treated LX-2 cells via targeting NR5A2, with clinical association with MAFLD.

BACKGROUND Metabolic-associated fatty liver disease (MAFLD) is a common chronic liver disease worldwide, with liver fibrosis serving as a major determinant of poor prognosis. While miR-885-5p shows dysregulated expression in numerous metabolic and liver disorders, its function in MAFLD has yet to be fully elucidated. T...