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Author

Shunwen Han

2 papers indexed here

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Aug 2026

Targeting ERO1A enhances antitumor immune response by recruiting CD8+T cells and synergizing with PD-L1 blockade in liver cancer.

Despite the availability of various treatment modalities for liver cancer, its mortality rate remains high. Immunotherapy represents an emerging approach for liver cancer. However, the response rate to single-agent immune checkpoint blockade therapy is suboptimal. Endoplasmic reticulum oxidoreductase 1-alpha (ERO1A), a...

Jing Mao, Xu Sun, Cai-Yun Chu et al. · 0 citations
Open access Jul 2026

Single-cell RNA-seq and spatial transcriptomics characterize CD8+ exhausted T cells in pancreatic ductal adenocarcinoma

Low SPP1 and PLAUR expression correlated with poor prognosis in TCGA-PAAD and two key LR pairs mediated crosstalk between cancer cells and CD8+ Tex cells, confirmed by immunofluorescence, spatial mapping, and protein docking.

Jing Mao, Chenxin Yan, Ying Mei et al. · 0 citations

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