Aerobic exercise and the gut-brain axis in Alzheimer's disease: Mechanistic perspectives, evidence appraisal, and future directions.
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder in which neuroinflammation, vascular dysfunction, metabolic disturbances, and impaired tissue resilience contribute to disease progression. Aerobic exercise is a widely applicable lifestyle intervention that has been increasingly investigated in AD...