An algorithmic Matching Score is described that evaluates cancer drugs’/drug combinations’ ability to address a patients’ entire next-generation sequencing/multi-omic-derived molecular profile and underscores the clinical importance of the precision medicine approach that maximizes matching of multiple molecular altera...
Ally Perlina, Subha Krishnan, K. Bush et al.· npj Genomic Medicine· 0 citations
The TRACK trial provides a scalable decentralized model for equitable access to precision medicine for patients with rare cancers while simultaneously generating data to drive a better understanding of rare cancers that otherwise may have limited treatment options.
J. Palma, Shumei Kato, M. Nikanjam et al.· Cancer Research· 0 citations
A patient with advanced BRAF-mutant ATC who recovered with a combination of the anti-PD1 nivolumab and the BRAF V600E targeted drug vemurafenib is shown, indicating further studies using biomarker-based gene- and immune-targeted agents, including in combination, are needed in ATC.
Noor Khalid, R. Kurzrock, Shumei Kato· npj Precision Oncology· 1 citation
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