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Shuang Zhang

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Open access Aug 2026

Proteome stability and dynamic protein complex profiling identified EEF1A1 as a novel translation regulator of autophagy and mitophagy

This work integrates thermal proteome profiling with co-aggregation analysis to monitor protein thermal stability and complex assembly dynamics in response to two canonical inducers: Torin 1, which activates autophagy via mTOR inhibition, and CCCP, a mitochondrial uncoupler that triggers mitophagy.

Shuang Zhang, Ya Zeng, Feng-Ming Li et al. · 0 citations

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