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Author

Shuangyin Han

2 papers indexed here

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Open access Aug 2026

Transcriptomic analysis identifies FABP5 as a candidate regulator of lipid accumulation in metabolic dysfunction-associated fatty liver disease

Objective The pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) is very complex, which has not been fully revealed as so far. This study aimed to identify differentially expressed genes involved in the pathogenesis of MAFLD using Oxford Nanopore Technologies (ONT) transcriptomic sequencing an...

Kai-Shuo Lv, Shu-Hang Zhong, Xiao-Qing Liu et al. · 0 citations
Open access Aug 2026

Gut microbiota-derived metabolites target C5AR1/KDM2A/HCAR3 axis in inflammatory bowel disease: a multi-machine learning algorithms and molecular docking study

Inflammatory bowel disease (IBD) is a chronic recurrent disorder. Gut microbiota-derived metabolites regulate intestinal homeostasis, but their molecular mechanisms in IBD remain unclear. Current studies lack systematic “microbiota-metabolite-target” network mining with multi-method validation. This study integrate...

Shanshan Hu, Lin Fu, Jing Gao et al. · 0 citations

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