Author

Shuangyan Jiang

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Review Open access Sep 2026

Engineered Source-Specific Extracellular Vesicles for Neurodegenerative Diseases: From Biological Barriers to Targeted Delivery Strategies

Abstract With the rapidly aging global population, neurodegenerative diseases (NDDs) present an escalating challenge to public health. The complex, self-perpetuating pathological network of NDDs, encompassing aberrant protein aggregation, chronic neuroinflammation, synaptic impairment, and mitochondrial dysfunction, si...

Hang-Lu Li, Shuang-Yan Jiang, Xin-Yi Liu et al. · International Journal of Nan... · 0 citations

Open access Jul 2026

A Tissue-Homologous Keratin-PBA Hydrogel Integrating Rationally Designed Nanomicelles Enables Microenvironment-Adaptive Repair of Chronic Diabetic Wounds.

A tissue-homologous, intelligently adaptive platform integrating intrinsic regenerative bioactivity with glucose-responsive therapeutic adaptability is presented, as evidenced by rapid wound closure, enhanced M2 macrophage polarization, robust neovascularization, improved collagen remodeling, and increased granulation...

Luyao Wang, Sheng-Chao Wang, I. Ullah et al. · Small · 0 citations

Jul 2026

Click-Chemistry-Based Antibacterial Hybrid Hydrogel with Sustained Puerarin Release for Diabetic Wound Healing.

In vivo diabetic mouse wound models confirmed that the MSFP hydrogel synergistically improved the wound microenvironment by establishing barrier protection, inhibiting bacterial growth, reducing inflammation, promoting M2 macrophage polarization, and enhancing vascularization.

Shuangyan Jiang, Hanglu Li, Pei Zhang et al. · ACS Applied Bio Materials · 0 citations