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Author

Shuaimin Lu

1 paper indexed here

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Aug 2026

pH-Controlled Stepwise Cyclization Enables Phage Display of Heterobridged Bicyclic Peptide Libraries

Phage-displayed bicyclic peptides offer access to conformationally constrained ligands with high affinity and specificity; however, current library designs are restricted to chemically identical crosslinkers, limiting structural and functional diversity. Here, we introduce a pH-controlled stepwise cyclization strateg...

Ming-Jing Ye, Ranfeng Ye, Lin Pan et al. · 1 citation

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