Author

Shuai-Xi Yang

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Open access Aug 2026

Integrative 3D genome and epigenomic analysis identifies TP53RK and SYBU as critical regulators of stemness and anti-tumor immunity in HCC.

Three-dimensional (3D) genome organization plays a fundamental role in governing gene regulation and tumor cell properties. However, how higher-order chromatin architecture regulates stemness in hepatocellular carcinoma (HCC) remains unclear. Here, we delineated the 3D chromatin landscapes of well- and poorly different...

Yan-Mei Yang, Peixian Li, Liangbo Zhao et al. · Cell Reports · 0 citations

Open access Aug 2026

Molecular subtyping of colorectal cancer based on aging-related gene network perturbation analysis and functional validation of MAP1B

Ageing-gene network perturbation defines three colorectal cancer subtypes and silencing MAP1B curbs invasion and migration and shrinks mouse tumors.

Wu Ning, Shuai-Xi Yang, Nan Qiao et al. · Translational Oncology · 0 citations