Shuai Wu

A glucose metabolism-targeted nanoplatform amplifies disulfidptosis-associated immunogenic cell death in triple-negative breast cancer

Disulfidptosis is a metabolism-dependent form of cell death driven by disulfide stress that induces actin cytoskeletal collapse in SLC7A11-high cells under glucose deprivation. However, strategies to therapeutically exploit this vulnerability remain underdeveloped. Given the high dependence of triple-negative breast ca...