Author

Shuai-Shuai Ni

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Review Open access Aug 2026

The gut microbiome organ

This review synthesizes current mechanistic and translational evidence to conceptualize the gut microbiome as an organ‐like functional system, delineate its structural and functional organization, and propose a framework for mapping, modeling, and therapeutically targeting microbiome‐derived circuits to support precisi...

Yang Bi, Wei-Bin Song, Maria Glymenaki et al. · iMeta · 0 citations

Open access Aug 2026

Acetoacetate–GPR43 axis epigenetically silences IL-6/CSF1 to restrict TAMs-driven metastatic lung cancer

A previously unappreciated collapse of acetoacetate homeostasis in lung cancer is uncovered, driven by the coordinated suppression of ketogenesis and increased ketolysis, resulting in a systemic acetoacetate deficiency.

Shuying Yuan, Biying Xiao, Shuai-Shuai Ni et al. · Journal of Translational Med... · 0 citations