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Shu-Pao Wu

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Sep 2026

Rational design of a near-infrared fluorescent probe for highly specific sensing carboxylesterase 2 and its applications in bioimaging.

Carboxylesterase 2 (CES2) is a clinically significant serine hydrolase that governs the metabolic activation and detoxification of numerous ester-containing drugs and prodrugs. Despite its pivotal role in liver and colorectal cancer progression, direct in situ imaging of CES2 activity remains challenging due to the sca...

Chia-Hung Li, Tsai-Xuan Lin, Shu-Pao Wu · 0 citations

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