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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shukun Chen

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2 papers indexed here

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Oct 2026

Coptisine Protects Against Cisplatin-Induced Acute Kidney Injury With Involvement of PI3K/Akt Signaling.

Cisplatin is an effective chemotherapeutic agent whose clinical use is limited by nephrotoxicity. This study investigated the protective effects of coptisine, a bioactive alkaloid from Coptis chinensis, against cisplatin-induced acute kidney injury (AKI). Network pharmacology was used to predict potential targets and p...

Chun-Yan Liu, Shu-Kun Chen, Ya-Ting He et al. · 0 citations
Aug 2026

Huangkui Capsule Effects in IgAN Through TLR4-Mediated Inflammatory Signaling.

Globally, immunoglobulin A (IgA) nephropathy (IgAN) is diagnosed more frequently than any other primary glomerular disorder and contributes substantially to the development of chronic kidney disease and end-stage renal disease. Although the Huangkui capsule, derived from Abelmoschus manihot, has demonstrated renoprotec...

Shukun Chen, Yan-Jun He, Ye Zhang et al. · 0 citations

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