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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shozeb Haider

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3 papers indexed here

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Open access Sep 2026

Microglial GRB2 is essential for brain ventriculogenesis and CSF homeostasis.

Microglia play essential yet poorly understood roles in brain development, including axon guidance, regulation of neurogenesis, and pruning of neuronal projections. Congenital hydrocephalus (CH), characterized by enlarged cerebrospinal fluid (CSF)-filled ventricles, is a leading cause of pediatric brain surgery, but it...

Phan Q. Duy, Benjamin C. Reeves, Huan-Xing Sun et al. · 0 citations
Open access Oct 2026

Structure-Guided Design of a Subnanomolar Dengue Virus NS4B Inhibitor.

Dengue virus nonstructural protein 4B (NS4B) is an essential regulator of viral replication but remains structurally unresolved, limiting drug discovery. Here, we combine modeling, ligand-based design, and experimental validation to enable structure-guided inhibition of NS4B. Comparative models across all four serotype...

Poomipat Laorsatiankul, Mohammad Hassan Baig, Shuang Chen et al. · 0 citations
Review Aug 2026

De novo chromatin remodelling variants in sporadic Chiari 1 malformation.

Exome sequencing may complement surgical evaluation of children with sporadic CM1, particularly when accompanied by neurodevelopmental concerns, informing prognosis and family counseling, and implicating genetically encoded dysregulation of cerebellar development as a central disease mechanism.

Neel H. Mehta, Garrett Allington, Evan Dennis et al. · 0 citations

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