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Author

Shogo Okazaki

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Open access Oct 2026

Adipocyte-specific mitochondrial intermediate peptidase (Mipep) deficiency protects against LPS-induced lethal inflammation through GDF15- and FGF21-independent mechanisms

Sepsis is a life-threatening organ failure driven by an abnormally uncontrollable inflammatory response to systemic infection. Recent studies have demonstrated that mild mitochondrial stress confers protection against lipopolysaccharide (LPS)-induced septic shock; however, the precise mechanisms linking mitochondri...

Tomoyoshi Fukuoh, Yuka Nozaki, Kota Nagasawa et al. · 0 citations

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