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Author

Shiori Ishiyama

2 papers indexed here

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Review Oct 2026

Early-Life Nutritional and Environmental Factors in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease: A DOHaD Perspective.

The Developmental Origins of Health and Disease (DOHaD) hypothesis posits that nutritional and environmental exposures during critical developmental periods, including fetal life, the suckling-weaning period, and early adulthood, strongly influence later disease risks. Research on DOHaD has expanded rapidly in recent y...

Haruka Adachi, Shiori Ishiyama, Kazuki Mochizuki · 0 citations
Open access Sep 2026

Excess glutamine in embryo culture media alters mitochondrial and autophagy-related dynamics associated with impaired postnatal development

The preimplantation period is a critical nutrient-sensing window influencing metabolic disease risk, as established by the developmental origins of health and disease theory (DOHaD). In this study, we examined the postnatal consequences of increased glutamine concentration, an important energy source, by altering embry...

Norermi Firzana Alfian, Yui Maruhashi, Masahiro Horizoe et al. · 0 citations

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