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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shimo Kang

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Open access Aug 2026

Beyond Respiration: Heme A Synthase (CtaA) Orchestrates Hydrogen Sulfide Production and Virulence via Metabolic Reprogramming in Staphylococcus aureus

This work identifies heme A synthase (CtaA) as a master regulator that couples respiratory metabolism with H2S biosynthesis, specifically under glucose-depleted conditions mimicking host niches such as abscesses and phagosomes and elucidate a novel metabolic-redox axis where CtaA governs H2S homeostasis to counteract h...

Jiahui Li, Mu He, Wanwan Hou et al. · 0 citations

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