Author

Shigeo Horie

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Open access Aug 2026

Evaluation of the efficacy of conditioned medium derived from quality- and quantity-cultured peripheral blood mononuclear cells for erectile dysfunction

Serum-free ex vivo quality- and quantity-cultured peripheral blood mononuclear cells (MNC-QQ), which can be manufactured within 1 week from a minimal volume of peripheral blood, demonstrate therapeutic efficacy in ED through multiple mechanisms, including angiogenesis, promotion of CCSMCs proliferation, and anti-fibrot...

Masafumi Furuya, T. Kataoka, Satomi Furukawa et al. · Regenerative Therapy · 0 citations

Open access Oct 2026

Clinical utility of combining the C-reactive protein-to-albumin ratio and systemic immune-inflammation index for prognostic assessment in metastatic renal cell carcinoma

Background Inflammation-based biomarkers may refine prognostic stratification in patients with metastatic renal cell carcinoma (mRCC). This study evaluated the prognostic value of the pretreatment C-reactive protein-to-albumin ratio (CAR) and systemic immune-inflammation index (SII) in patients with mRCC receiving firs...

Nobuhito Muramoto, Masayoshi Nagata, Hisashi Hirano et al. · PLoS ONE · 0 citations