Author

Shifeng Wu

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Jul 2026

An Explicit World Model Based on Data-First Ontology: DaoQL Multimodal Storage Validation and Counterfactual Reasoning Evaluation

This paper proposes data-first ontology: LLMs are treated as reasoning and language engines, while deterministic knowledge is moved into an explicit multimodal database, DaoQL, formalizing an explicit world model and showing that, under rule independence, deterministic evaluation, and fixed conflict resolution, explici...

Zhanbo Li, Shifeng Wu, Xiangjin Meng et al. · arXiv.org · 0 citations

Open access Jul 2026

SPARC: A Graph-based Optimization Framework for Directional Trajectory Reconstruction Across Ordered Single-Cell Conditions

SPARC is presented, a graph-based optimization framework that quantifies similarity in a shared high-dimensional latent space and reconstruct directional trajectories under biological constraints and is the first to propose a “cross-organ bone-like microenvironment” hypothesis.

Shifeng Wu, W. C. Walker, Carolyn A. Martin et al. · bioRxiv · 0 citations