This work introduces a geometric framework for analyzing the spatiotemporal evolution of gene expression networks through embeddings in Gromov--Wasserstein (GW) space and demonstrates that hypernetwork representations successfully record salient biological changes across time.
M. Oliver, K. Hohmeier, Tuyến Trần et al.· 0 citations
The proposed Wasserstein Mahalanobis distance approximates the classical Mahalanobis distance between the transformed latent means and holds up to controlled higher-order error terms for general smooth transformations.
This review comprehensively summarizes the multifaceted roles of major histone modifications, including acetylation, methylation, ubiquitination, phosphorylation, and emerging metabolism-linked acylations, in governing critical DNA-templated processes such as replication, transcription, and the DNA damage response.
Ling-Li Wang, Shi-Ying Li, Xiao-Yan Hu et al.· Precision Clinical Medicine· 0 citations
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