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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Shi-Yi Ge

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Open access Sep 2026

Berberine Prevents and Reverses Gastric Spasmolytic Polypeptide-Expressing Metaplasia by Modulating M2 Macrophage Polarization

Findings provide preclinical evidence supporting berberine as a candidate therapeutic agent for SPEM by preventing and reversing tamoxifen-induced gastric SPEM by inhibiting M2 macrophage polarization and infiltration and regulating the JAK-STAT/NF-κB pathway and S100A6 expression.

Jia-Lei Li, Shi-Yi Ge, Xing-Xing Zhou et al. · 0 citations

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