Author

Shi-Wu Zhang

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Open access Sep 2026

Cofilin/RhoA and CREB synergistically promote invasion and migration of polyploid giant cancer cells in colorectal cancer

Colorectal cancer (CRC) is associated with high mortality and poor survival. Polyploid giant cancer cells (PGCCs) are a subset of cancer cells that drive tumor initiation and progression. In this study, high-concentration CoCl₂ treatment was used to induce Hct116 and LoVo cells to form PGCCs with daughter cells (PDCs),...

Yi-Di Ning, Kai Liu, Jing Xu et al. · Journal of Cancer · 0 citations

Review Sep 2026

Proximity labeling: A powerful tool for mapping protein interactions.

Protein-protein interactions (PPIs) are fundamental to cellular regulation, and their dysregulation contributes to numerous diseases. Conventional approaches for studying PPIs often lack sufficient spatial and temporal resolution and are limited in capturing weak, transient, or context-dependent molecular associations....

Hua Yin, Shi-Wu Zhang, Shu-Lin Liu et al. · Biosensors & bioelectronics · 0 citations